How to Use

To ensure the safe use of Promethazine, let your doctor know if you have a history of the following conditions:

• Sulfite allergy
• Seizures
• Glaucoma
• Liver disease
• Asthma, sleep apnea, chronic obstructive pulmonary disease or any other breathing problem
• Weak immune system
• Enlarged prostate
• Problems passing urine
• Heart disease
• Hypocalcaemia
• Adrenal gland tumor
• High blood pressure
• Serious Promethazine side effects

Promethazine should be used with a prescription. Do not take a larger or smaller dose than recommended. Your doctor may change your dose occasionally to achieve the best results.

Promethazine is taken before meals or at bedtime. If being treated for motion sickness, the dose is taken at least an hour before travelling. For surgery, the drug is taken a night before the planned surgery.

The frequency of taking this medicine depends on the conditions being treated. Use a dosing syringe to measure the dose. A pharmacist will provide you with the proper dose-measuring spoon or dosing syringe.

Report changes in weight and other new and worsening side effects and symptoms. 

FDA Pregnancy Classification

Category C

It is unknown if Promethazine can harm an unborn baby. Let your doctor know if you are pregnant or plan on becoming pregnant soon. It is also unknown if Promethazine can pass into breast milk. Consult your doctor if you are breastfeeding a baby. 

Storage

Store at room temperature and away from light, heat and moisture.

Side Effects

• Elevated or slowed heartbeats
• Seizures
• Severe drowsiness
• Shallow breathing
• Light-headedness
• Jaundice
• Uncontrolled muscle movements
• Easy bruising
• Sudden weakness
• Ringing in the ears
• Double vision
• Dry mouth
• Sleeping problems

Safety

In case of uncontrollable movements or twitching of the lips, tongue, arms, legs, face or eye lids, stop using Promethazine and contact your doctor. These might be the early signs of serious side effects.

Promethazine should not be given to a child below the age of 2. The medicine can cause severe breathing problems or even death in very young kids. Always contact your doctor before using this medication.

Some of the side effects of Promethazine will impair your judgment and reactions. Avoid activities that require alertness. You should also avoid alcohol while on this drug in order to avoid serious interactions. Your doctor must also know of all the medications you are using before a prescription is given.

Interactions

Promethazine interacts with 1076 drugs.